Signal transduction and membrane traffic: The PITP/phosphoinositide connection
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چکیده
منابع مشابه
Signal transduction and membrane traffic: The PITP/phosphoinositide connection
Phosphatidylinositol (Ptdlns) transfer protein (PITP) is a ubiquitous and abundant cytosolic protein that was discovered some 25 years ago because it can exchange Ptdlns and phosphatidylcholine (PtdCho) between lipid bilayers (for review see Wirtz, 1991). This in vitro activity suggested an in vivo function of PITP in transport of these phospholipids from the site of their synthesis in the endo...
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W e thank Dr. J. S. Morrow for spectrin constructs; Dr. L Rameh, Dr. A. Toker and Dr. L.C. Cantley for the Btk PH domain construct; Dr. R Lefkowitz for the oxysterol-binding protein PH construct; and Dr. T. Petrucci, Dr. R Kahn, Dr. j. Saraste and Dr. P. Hauri for antibodies. This work was supported by Telethon, CNR and AIRC. A G . is the recipient of a fellowship from the Centro di Fomazione e...
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ژورنال
عنوان ژورنال: Cell
سال: 1995
ISSN: 0092-8674
DOI: 10.1016/0092-8674(95)90525-1